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HITACHIInspire the NextTechnical ReportAS/MSD-008 Liquid ChromatographC2015 Hitachi High-Tech Science Corporation Analysis of Organic Acids by MS Detector chromaster 5610 MS Detector is a mass detector with new concept, designed for LC users, andit is different from conventional mass spectrometers. Organic acids greatly affect the tastes andflavors of foods and therefore, are frequently analyzed for the purpose of research anddevelopment, quality control, etc. In addition to food products, various products such as drugs,culture liquids, plating solutions, and cosmetics are being analyzed. This time, six organic acidsare separated by using a HILIC column and detected by Chromaster 5610 MS detector, and theexample is introduced here. 5610 MS Detector LC-MS Analysis of 6 Organic Acids Table 2 Analytical Conditions for HPLC Column Inertsil HILIC (3 um)4.6 mml.D. x250 mm Mobile phase CH,OH/ 10 mmol/L CH,COONH4=90/10 Flow rate 1.0 mL/min (250:1 sprit) Injection vol. 10pL Figure 1 Mass Spectra and SIM Chromatograms of 6 Organic Acids
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