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杂质中使用多中心切割二维液相色谱进行杂质分析的方法开发检测方案(自动进样器)

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检测项目 使用多中心切割二维液相色谱进行杂质分析的方法开发

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The analysis of impurities is of great importance during the development and production of pharmaceuticals and fi ne chemicals. This Application Note shows that multiple heart-cutting 2D-LC is ideally suited for method development for impurity analysis of pharmaceuticals and fi ne chemicals. Using the Agilent 1290 Infi nity 2D-LC Solution, every peak detected after the fi rst-dimension separation was heart-cut and transferred to a second-dimension separation with different selectivity. This approach enabled the discovery of possible coeluting compounds. In addition, the identity of impurities could be confi rmed by spiking the sample with the suspected impurity.

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安捷伦科技(中国)有限公司为您提供《杂质中使用多中心切割二维液相色谱进行杂质分析的方法开发检测方案(自动进样器)》,该方案主要用于其他中使用多中心切割二维液相色谱进行杂质分析的方法开发检测,参考标准《暂无》,《杂质中使用多中心切割二维液相色谱进行杂质分析的方法开发检测方案(自动进样器)》用到的仪器有Agilent 1290 Infinity II Multisampler。

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