上皮粘连调控蛋白ESRP2抗体产品介绍

中文名称：上皮粘连调控蛋白ESRP2 多克隆抗体 英文名字：ESRP2 Polyclonal Antibody 供 应 商：远慕生物 背景资料：ESPR2 is an epithelial cell-type-specific splicing regulator. ESRP2 (Epithelial Splicing Regulatory Protein 2) is a Protein Coding gene. Among its related pathways are Signaling by FGFR2 and mRNA Capping. 宿主物种:兔 交叉反应:人,小鼠,大鼠,狗,奶牛 克隆类型:多克隆 分 子 量:78kDa 浓 度:1mg/1ml 亚 型:IgG 细胞定位:细胞核 免 疫 原:KLH conjugated synthetic peptide derived from human ESRP2 纯化方法:蛋白A亲和纯化 产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 尚未测试其他应用; 实际稀释浓度可根据用户的具体用途决定。 储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol 保存条件:4℃运输，-20℃保存，避免反复冻融 应用领域:细胞生物 细胞粘附分子 细胞类型标志物 表观遗传学 保存建议 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 产品介绍 background: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Function: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Subcellular Location: Nucleus. Tissue Specificity: Epithelial cell-specific. Similarity: Belongs to the ESRP family. Contains 3 RRM (RNA recognition motif) domains. Database links: UniProtKB/Swiss-Prot: Q9H6T0.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.