cAMP的荧光检测

Adenosine 3´, 5´-cyclic monophosphate (cyclic AMP, cAMP) is a universal secondary messenger that connects changes in the extracellular environment, as detected by cell surface receptors, to changes in the nucleus, which results in altered patterns of gene expression. It is involved in intra- and inter-cellular signaling in organisms as diverse as bacteria, slime mold, fruit fly and humans. Cyclic AMP is produced from ATP by the enzyme adenylate cyclase (AC) and is hydrolyzed by cyclic AMP phosphodiesterases. Activation of these enzymes allows for the tight control over the levels of cAMP inside the cell.