Rat anti – guinea pig Tumor Necrosis Factor α

Rat anti – guinea pig Tumor Necrosis Factor α Collect Sample – serum or blood plasma Package size: 96 determinations Catalogue No.: QRCT –881354EIA \ UTL Storage: 2 - 8 °C I. INTRODUCTION TNF contain form of two kinds of numerators, a the kind call the TNF α , another kind to call the TNF β .Single that be activated by germs many sugars of TNF α the cell produce, and can cause the tumor to organize to bleed the bad dead, and also call the disease the quality vegetable;( cachectin)Lymphoid cell that TNF β produce, have the tumor to kill to harm from the antigen or silk original incitement and the immunity regulate the function, and again call the lymphoid toxin.( lymphotoxin, LT)Despite two type TNFs contain top of different cell source, DNA level to also only reach 28% of that sour preface row of, but both join together in same alike suffer, and have very alike biology function.Gene that person TNF the α all locate the No.6th chromosome with the β .The molecular weight of the mature TNF α is roughly 17 kD, but the TNF β slightly report the the quality, for 2025 kD.The TNF suffers to exsit in almost have of have the cell the surface, and now and already discovers two kinds of TNFs suffering. The can directly kill the wound lump the cell in the TNF but have to hurt the normal cell, ratio chemotherapy medicine the poison is small, rhTNF may the other cell factor is sooner large quantity application in clinical.Alone use the TNF to use to have great capacity, not easy winning result that like, get often because of can't bear to is side effect by its but the abeyance use the medicine.Repress the function the medicine and TNF the tumor that other have cell factor( such as IL-2, IFN...etc.) or some anti- tumors to unite the application, since can reduce the using of every kind of medicine to measure