核突触蛋白抗体

核突触蛋白抗体 Background: The synucleins, including alpha-synuclein (also designated NACP for nonamyloid component precursor),beta-synuclein (also designated PNP 14 for phospho-neuroprotein 14)and gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1)are presynaptic protein abundant in neurons. alpha-synuclein, a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of alpha-synucleinand beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson’s disease, a mutant form of alpha-synuclein has been found and gamma-synuclein is associated with axonal pathology. Also known as: Alpha synuclein; Alpha-synuclein, isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid , precursor of; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease familial 1; PD 1; PD1; SNCA; Snca synuclein, alpha (non A4 component of amyloid precursor); Synuclein alpha; Synuclein, alpha (non A4 component of amyloid precursor);