激活素受体2B抗体

激活素受体2B抗体 Background: Activin receptor type-2B( Activin receptor type IIB; ACTR-IIB ) On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. [Subcellular Location] Membrane; Single-pass type I membrane protein. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Also known as: Activin A receptor type IIB; Activin receptor type 2B; ActR IIB; ACTR-IIB; ActRIIB; ACVR 2B; ACVR2B; MGC116908; AVR2B_HUMAN; Activin receptor type IIB; Activin receptor type-2B; HTX4;MGC116908.