通过Biotage微波合成仪以5-胺基吡唑，醛和丙酮为原料进行多组分合成吡唑并吡啶及其相关衍生物by耐士科技

Abstract—The reactions of 3-substituted 5-aminopyrazoles with arylidenepyruvic acids and their synthetic precursors, pyruvic acid and aromatic aldehydes, were studied. Several different reaction pathways for these cyclocondensation reactions were established depending on the reaction conditions and building block selection. The formation of pyrazolo[3,4-b]pyridine-6-carboxylic acids as major products and related compounds was discussed from the mechanistic point of view.