90Plus Zeta测量应用案例-2016-28

Acute myeloid leukaemia (AML) is a severe disease due to the fast and excessive production of abnormal and immature myeloid blasts that causes an increased risk of anemia, bleeding and infections. The use of drug delivery systems is an efficient approach to overcome multidrug resistance in AML cells and can be targeted to these cells by the incorporation of homing molecules in their surface (e.g., attachment of folate (FOL) molecules that binds to folate receptors selectively expressed in leukaemia cells of approximately 70% of AML patients).