在同一台显微光谱仪上用拉曼和红外光谱对药片中的药物活性成分和赋形剂进行成像和表征

The different components of this pharmaceutical sample can be characterized easily by Raman spectroscopy and the comparison with spectra from our libraries allowed us to identify some of these molecules. A good spectral discrimination could be obtained as the characteristic spectral fingerprints have exclusive features. The Raman imaging technique is a very powerful tool as shown here, as it also enables to characterize the spatial distribution of the components with a high spatial resolution. The complementary results obtained by FTIR spectroscopy on the sample confirm the presence of lactose and allows the identification of the third component also observed by Raman spectroscopy. The combination of FTIR and Raman analysis on the same spectrometer represents a powerful analytical tool to readily record both IR and Raman vibrational information from a same sample position.