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The combination of SPRi with MALDI-MS on an array platform is a powerful tool for affinity separation and identification of specific ligands from complex solutions. A versatile sensor surface has been designed to allow SPR ligand fishing and MALDI-MS identification of the retained ligand. SPRi-slideTM transfer from SPRi-PlexTM to MALDI-MS plate is easy and MS analysis is directly carried out on the micro-array biochip. High-through-put multiplexed analysis with spatial resolution is permitted with this aray platform.
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