C&EN封面故事 - 质谱成像探秘药物在组织中的分布

Sometimes it's not enough to know how much drug has reached a particular tissue. Sometimes you need to know where in that tissue the drug has gone. To answer that and other questions, pharmaceutical companies are turning to imaging mass spectrometry. It allows pharma scientists to collect information about drug distribution much earlier in the discovery process than previously possible. The resulting pictures are helping drug developers prevent toxicity and off-target effects.