使用SOLAμ板样品制备和TSQ Endura三重四极杆质谱仪联用进行临床研究中血浆甲基丙二酸的定量检测

We demonstrated a sensitive and robust method for quantifying MMA in plasma that provides a wide dynamic range, while employing simple and economical sample preparation. With the short run time and data acquisition window, this analytical method can be put into use on a 4-channel Thermo Scientific™ Transcend™ II LC system to address high-throughput analysis (50 samples/hour) requirement in clinical research.