Ti6A/4v生物金属上紧密粘合的丝素蛋白涂层，可改善湿润性和相容的机械性能

• A facile, controllable and low-cytotoxic method of physically depositing and stabilizing silk fibroin using HFIP solvent onto Ti biometal TC4 was established. • The interface adhesion strength was determined through advanced centrifugal measurement, and high silk fibroin (SF)-TC4 adhesion strength of 7 MPa was achieved with optimized substrate roughness (Ra~1 μm). • The water wettability of TC4 was improved significantly with SF coatings. • The SF-TC4 coating-substrate system proved to improve osteoblast cell viability and growth.