方案摘要
方案下载应用领域 | |
检测样本 | |
检测项目 | |
参考标准 |
We have shown an easy-to-use technique (no sample preparation, no chromatography) that shows extraordinary potential for the quantitative analysis of drugs of abuse in forensic toxicology when coupled to the TSQ Quantiva triple quadrupole mass spectrometer, all in much shorter timeframes than it is possible using liquid chromatography techniques. Quantitative analysis of several drugs in a mix from 7 μL of urine is demonstrated, with LODs down to 0.5 ng/mL and LOQs slightly higher and compound dependent. As the electrospray signal from paper spray lasts ~35 s, it can accommodate many SRM transitions per sample. This, coupled to available faster scanning speed on the TSQ Quantiva mass spectrometer, opens the stage for the analysis of more complex mixtures. To investigate possible interferences in the SRM transitions, isolation widths of 0.2 amu or alternative transitions should be investigated on the TSQ Quantiva mass spectrometer. Compounds affected by matrix effects might benefit from alternative solvent/modifier combinations and advances in paper spray substrate development.
新品 优选 Orbitrap Ascend Editions Tribrid系列超高分辨质谱仪
型号:Orbitrap Ascend Editions Tribrid系列超高分辨质谱仪新品 优选 Thermo Scientific™ Stellar™质谱仪
型号:Thermo Scientific™ Stellar™质谱仪新品 优选 Vanquish™ Access HPLC系统
型号:Vanquish Access HPLC 系统新品 优选 赛默飞Inuvion离子色谱系统
型号:Dionex Inuvion高压离子色谱Inuvion快速测定自来水中的常见阴离子
高压离子色谱Inuvion快速测定生活饮用水中的亚氯酸 盐、溴酸盐、氯酸盐、二氯乙酸和三氯乙酸
Thermo Fisher Scientific iCAP TQe ICP-MS/MS测定土壤和沉积物多种元素
相关产品
赛默飞Inuvion离子色谱系统
TSQ 9610 三重四极杆 GC-MS/MS
赛默飞气相色谱仪Trace 1600
ISQ 7610™单四极杆 GC-MS
Vanquish Neo UHPLC 系统
赛默飞TSQ Quantis Plus 三重四极杆质谱仪
赛默飞TSQ Altis Plus 三重四极杆质谱仪
赛默飞TSQ Fortis Plus三重四极杆质谱仪
Orbitrap Exploris MX 质量检测器
Orbitrap IQ-X Tribrid 质谱仪
赛默飞三重四极杆 LC-MS质谱系统TSQ Altis(LC-QQQ)
Orbitrap Exploris GC 气质联用仪
Orbitrap Exploris GC 240
新一代Orbitrap Exploris 240质谱仪
Thermo Scientific™ Orbitrap Exploris 120
关注
拨打电话
留言咨询