TSQ Altis 超高灵敏度多兽残分析

2017/11/21   下载量: 7

方案摘要

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应用领域 制药/生物制药
检测样本 兽用药
检测项目 含量测定>色谱法
参考标准 赛默飞

To develop a sensitive, robust, reproducible LC-MS/MS assay for determination and quantitation of a mixture of compounds of pharmaceuticalinterest in human plasma and plasma from preclinical animal species.

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Small molecules represent a significant proportion of drug discovery and development in the search for new chemical entities, in addition to the extensive work involved in the regulatory filings of generics. Targeted quantitation assays are a critical part of an optimal workflow, which is required to successfully develop a small molecule drug. These targeted quantitation analyses must be done in biological matrices, which can often create analytical challenges. In this study, we report the development of a sensitive, robust, reliable, and reproducible LC-MS/MS assay for multiple drug standards in rat plasma.

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