高选择性和高精度的人血浆中去氨加压素分析

2018/03/13   下载量： 7 次

方案摘要

方案下载
应用领域 医疗/卫生
检测样本 全血/血清/血浆
检测项目
参考标准 Neudert, L.; Zaugg, M.; Wood, S.; Struwe, P. A High Sensitivity Dual Solid Phase Extraction LC-MS/MS Assay for the Determination of the Therapeutic PeptideDesmopressin in Human Plasma

The results presented demonstrate the successful development of an accurate, precise, and selective SPE-LC-MS/MS method for the analysis of desmopressin from human plasma. Use of micro-elution SPE allowed for concentration of the sample prior to analysis without the need for post-extraction processing. Utilizing SOLAµ mixed-mode SPE provided both a clean and repeatable extract across the concentration range.

方案下载
配置单
方案详情

SOLAµ WCX, Accucore Vanquish, Vanquish, desmopressin, LC-MS/MS,
UHPLC, mixed-mode SPE, solid-phase extraction, micro-elution, peptides,
bioanalysis, biopharma

To describe an accurate, precise, high-throughput workflow for the analysis
of desmopressin from human plasma utilizing micro-elution solid-phase
extraction (SPE), followed by liquid chromatography separation coupled to
triple quadrupole mass spectrometry detection (LC-MS/MS).

The results presented demonstrate the successful
development of an accurate, precise, and selective
SPE-LC-MS/MS method for the analysis of desmopressin
from human plasma. Use of micro-elution SPE allowed
for concentration of the sample prior to analysis without
the need for post-extraction processing. Utilizing SOLAµ
mixed-mode SPE provided both a clean and repeatable
extract across the concentration range.

上一篇 高压离子色谱Inuvion快速测定自来水中的常见阴离子
下一篇 快速测定动物血浆中的治疗性抗体

文献贡献者

赛默飞色谱与质谱
钻石会员 丨 第23年
查看全部资料
相关仪器 更多
相关方案
更多

相关产品

当前位置： 赛默飞色谱与质谱 方案 高选择性和高精度的人血浆中去氨加压素分析

关注

拨打电话

留言咨询