Method Development and Evaluation for Multiresidue Pesticide analysis in Foods Using the 6475 Triple Quadrupole LC/MS System

2023/08/15   下载量: 0

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应用领域 食品/农产品
检测样本 食用植物油
检测项目 其他>方法开发
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This application note describes the development and valuation of a comprehensive LC/MS/MS method for over 500 pesticide analyses in three food matrices (wheat, olive oil, and black tea). The work was completed using the Agilent 6475 triple quadrupole LC/MS (LC/TQ) system coupled with the Agilent 1290 Infinity II Bio LC system and MassHunter Workstation 12.0.

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This application note describes the development and evaluation of a comprehensive LC/MS/MS method for over 500 pesticide analyses in three food matrices (wheat, olive oil, and black tea). The work was completed using the Agilent 6475 triple quadrupole LC/MS (LC/TQ) system coupled with the Agilent 1290 Infinity II Bio LC system and MassHunter Workstation 12.0.


The Agilent 6475 triple quadrupole LC/MS instrument contains hardware and software improvements to the legacy systems:

– Artificial Intelligence (AI)-based tuning and calibration

– Active system monitoring with early maintenance feedback (EMF)

– Reflexive reinjection logic with intelligent reflex (iReflex)

– Maintenance and method development automation

– Enhanced MS1 and MS2 resolution with narrow isolation mode

– Adherence to 21 CFR Part 11 and Annex 11 compliance guidelines


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下一篇 An end-to-end software algorithm for LC/MS/MS method development, optimization, and QA/QC deployment

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