方案摘要
方案下载应用领域 | 医疗/卫生 |
检测样本 | 其他 |
检测项目 | |
参考标准 | 表征 |
Like ITC, DSC is a valuable approach for studying binding between a biological macromolecule and a ligand such as another biopolymer or a drug. Unlike ITC, DSC allows the thermodynamics that drive binding to be correlated, at least to a degree, with conformational changes in the macromolecule caused by the binding reaction. DSC is particularly useful for characterizing very tight or slow binding interactions. DSC also allows characterization of binding reactions that are incompatible with the organic solvent requirements of some ITC experiments (i.e., where ligand solubility for an ITC experiment requires concentrations of organic solvent not tolerated by the protein).?
Like ITC, DSC is a valuable approach for studying binding between a biological macromolecule and a ligand such as another biopolymer or a drug. Unlike ITC, DSC allows the thermodynamics that drive binding to be correlated, at least to a degree, with conformational changes in the macromolecule caused by the binding reaction. DSC is particularly useful for characterizing very tight or slow binding interactions. DSC also allows characterization of binding reactions that are incompatible with the organic solvent requirements of some ITC experiments (i.e., where ligand solubility for an ITC experiment requires concentrations of organic solvent not tolerated by the protein).
利用微量热技术研究病毒结构与宿主细胞受体结合反应
等温量热法研究水泥水化
等温微量热法研究生物制品长时间稳定性评价
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