ABAT antibody|100ul|3359-1-上海希美化学有限公司

ABAT antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

3359-1

CAS号：

产品详情

ABAT antibody
Cat.#: 3359-1
Rabbit Monoclonal Antibody
Clone ID: EPR4433
Swiss Prot: P80404
Mol Weight: 50kDaSize: 100ul
Description
ABAT (4-aminobutyrate aminotransferase) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities (1).

Recommended Applications
WB, IHC, IP

Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
IHC: 1:250 - 500
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only

Products Data

Western blot analysis on (A) HepG2, (B) SH-SY5Y, (C) fetal liver, (D) rat brain, (E) rat kidney, and (F) mouse brain lysates using anti-ABAT RabMAb (cat. #3359-1).
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ABAT RabMAb (cat. #3359-1).
Specificity
A synthetic peptide corresponding to residues in human ABAT was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ABAT antibody, FLJ17813 antibody, FLJ30272 antibody, GABA-AT antibody, GABAT antibody, NPD009 antibody, 4-aminobutyrate aminotransferase, mitochondrial antibody, L-AIBAT antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.

Business information

工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】