ABI1 Phospho(pY435)antibody|100ul|3244-1-上海希美化学有限公司

ABI1 Phospho(pY435)antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

3244-1

CAS号：

产品详情

ABI1 Phospho(pY435)antibody
Cat.#: 3244-1
Rabbit Monoclonal Antibody
Clone ID: EP3954
Swiss Prot: Q8IZP0
Mol Weight: 55kDa
Size: 100ul

Description
ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling (1). In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA, and widely expressed, with highest expression in brain (2).

Recommended Applications
WB, ICC, IP, FC

Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
ICC: 1:250 - 500
IP: 1:10 -100
FC: 1:10 - 100

Species Reactivity
Human

Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on Jurkat cell lysates using anti-Phospho-ABI1 (pY435) RabMAb (cat. #3244-1). Cells were either (A) untreated (B) treated with Pervanadate.

Specificity
A phospho specific peptide corresponding to residues surrounding tyrosine 435 of human ABI1 was used as an immunogen. This antibody only detects ABI1 phosphorylated at tyrosine 435.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ABI1 antibody, ABI-1 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, Abl interactor 1 antibody, Spectrin SH3 domain-binding protein 1 antibody, e3B1 antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.
2. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2010)

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】