3-hydroxyanthranilate 3,4-dioxygenase antibody|100ug|S0948-上海希美化学有限公司

产品详情

3-hydroxyanthranilate 3,4-dioxygenase antibody
Cat.#: S0948
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P46952
Mol Weight: 32.56kDa
Size: 100ug

Description
3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

Sample(30ug of whole cell lysate)
A:Hep G2
12% SDS PAGE
diluted at 1:500

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 228 of Human HAAO

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
HAAO antibody, 3-HAO antibody, HAO antibody, 3-hydroxyanthranilate 3,4-dioxygenase antibody, 3-hydroxyanthranilic acid dioxygenase antibody

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Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：
规格：	100ug
货号：	S0948
CAS号：