人内皮素-2(EDN2)|1mg|HOR-308-上海希美化学有限公司

产品详情

Human Endothelin-2(人内皮素-2)
Human EDN2
Catalogue Number：HOR-308

Synonyms:
EDN2, EDN-2, vasoactive intestinal contractor peptide, VIC, ET-2, Endothelin-2, Preproendothelin-2, PPET2, ET2.
Introduction:
Endothelin-2 is a Hypoxia-induced Autocrine Survival Factor for Breast Tumor Cells. The synthesis of EDN2 by human kidney carcinoma cells is decreased by EGF. EDN2 is a chemoattractant for macrophages and THP-1 monocytic cells. Chemotaxis towards EDN2 is via the MAPK pathway: p44 and p42 are phosphorylated when THP-1 cells are stimulated with EDN2. Migration to EDN2 is inhibited by hypoxia and by pertussis toxin. EDN2 leads to activation of macrophages. EDN2 shares a similar peptide sequence with chemokines and may signal via a similar receptor and MAPK-mediated pathway. Furthermore, EDN2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.
Description:
EDN2 contains 21 amino acids having a molecular mass of 2546.97 Dalton.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
The protein (1mg/ml) was lyophilized with no additives.
Solubility:
It is recommended to reconstitute the lyophilized EDN2 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Stability:
Lyophilized EDN2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EDN2 should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 95.0% as determined by RP-HPLC.
Amino acid:
sequence Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
相关产品：

EDN1 人内皮素-1 HOR-307 Human Endothelin-1
EDN2 人内皮素-2 HOR-308 Human Endothelin-2
EDN3 人内皮素-3 HOR-309 Human Endothelin-3

人内皮素-2(EDN2)由上海希美化学有限公司为您提供，货号HOR-308，规格：1mg，CAS号：，如您想了解更多关于人内皮素-2(EDN2)价格、人内皮素-2(EDN2)结构式、批发、用途等信息，欢迎咨询。除供应人内皮素-2(EDN2)外，还可为您提供大鼠内皮素1(ET-1)ELISA Kit、人内皮素-1（EDN1）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：
规格：	1mg
货号：	HOR-308
CAS号：