AFP(N-term)antibody|100ul|1816-1-上海希美化学有限公司

AFP(N-term)antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

1816-1

CAS号：

产品详情

AFP(N-term)antibody
Cat.#: 1816-1
Rabbit Monoclonal Antibody

Clone ID: EP1016Y
Swiss Prot: P02771
Mol Weight: 70kDa
Size: 100ul

Description
Alpha-fetoprotein (AFP) is a serum glycoprotein protein produced in the liver or yolk sac of fetal staged mammals. AFP synthesis is minimal after birth and trace amount is expressed in the adult liver (1). AFP gene expression is regulated by the interactions between steroid hormone receptors and transcriptional factors in separate signal transduction pathways (2). AFP functions as a binding and transporting ligand and cell growth regulator. Elevated expression level of AFP has been implicated in colorectal, ovarian, pancreatic, testicular, and certain liver cancers. High levels of AFP are also seen in some diseases such as hepatitis and colitis. AFP is used as a screening marker for fetal abnormalities in pregnant women such as Down syndrome. Recently, AFP has been introduced as an anti-cancer drugs-ligand carrier, transporting drugs to target tumor cells, increasing anti-tumor efficiency (3).

Recommended Applications
WB, IP

Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
IP: 1:50

Species Reactivity
Human

Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on HepG2 cell lysate using anti-AFP RabMAb (cat. # 1816-1).

Specificity
A synthetic peptide corresponding to residues near the N-term of human AFP was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
AFP antibody, FETA antibody, HPAFP antibody, Alpha-fetoprotein antibody, Alpha-1-fetoprotein antibody, Alpha-fetoglobulin antibody

Description References
1. Wang XW, et al. World J Gastroenterol 7:345-351, 2001.
2. Chen H, et al Crit Rev Eukaryot Gene Expr, 7:11-41, 1997.
3. Zheng AI, et al. CJC 22:108-111, 2003.

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】