| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 100ul |
| 货号： | 2358-1 |
| CAS号： |
Alpha-Actinin 1(ACTN1)antibody
Cat.#: 2358-1
Rabbit Monoclonal Antibody
Clone ID: EP2528Y
Swiss Prot: P12814
Mol Weight: 100kDa
Size: 100ul
Description
Alpha-actinin is a ubiquitously expressed protein found in numerous actin structures. It consists of an N-terminal actin binding domain, a central rod domain, and a C-terminal domain and functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments and also serves as an interaction site for several cytoskeletal and signaling proteins (1). Alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. Alpha-actinin-1 and -4 (ACTN1, ACTN4) are non-muscle isoforms version of ACTN. These isoforms are commonly expressed in filopodia, lamellipodia, stress fibers, sites of adhesion and intercellular contacts (2).
Recommended Applications
WB, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:500 - 1000
ICC: 1:100-250
IP: 1:40
FC: 1:40
Species Reactivity
Human
Cross reactivity for this product was determined by western blot.
Products Data
A. Western blot analysis on (A) NIH 3T3 (B) human skeletal muscle tissue (C) human heart tissue lysates using anti-alpha-actinin 1 RabMAb (cat.# 2358-1), dilution 1:1000.
Specificity
A synthetic peptide corresponding to residues on the C-terminus of human Alpha-Actinin 1 was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ACTN1 antibody, FLJ40884 antibody, FLJ54432 antibody, Alpha-actinin-1 antibody, Alpha-actinin cytoskeletal isoform antibody, F-actin cross-linking protein antibody, Non-muscle alpha-actinin-1 antibody
Description References
1. Ylanne J, et al. Structure 9(7):597-604, 2001
2. Otey, CA and Carpen O. Cell Motil. Cytoskeleton 58:104-111, (2004).
相关产品
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
3-D Life Dextran-PEG Hydrogel Kit
3-D Life Dextran-CD Hydrogel Kit（3D 细胞培养 葡聚糖马来酰亚胺-聚乙二醇仿生水凝胶试剂盒）
3-D水凝胶PEG-Link（聚乙二醇交联剂）（3D细胞培养 PEG 交联物（非降解））
3-D Life CD-Link（3D细胞培养 CD 交联物（可细胞降解））
3-D Life Maleimide-Dextran Set（3D 细胞培养葡聚糖马来酰亚胺聚合物）
3D 细胞培养RGD多肽（粘附剂）3-D Life RGD Peptide
3-D Life Scrambled RGD Peptide
Pig C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Mouse C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Human C-type lectin domain family 5 member A(CLEC5A)ELISA kit
无形体IgM免疫荧光试剂盒
牛甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
鸡甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
人羰基还原酶-4(CBR4)
1820
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
工商信息
信息已认证
联系方式
详细地址
关注
拨打电话
留言咨询
