供货周期: | 一周 |
品牌: | |
规格: | 100ul |
货号: | 2310-1 |
CAS号: |
Alpha-Actinin 2(ACTN2)antibody
Cat.#: 2310-1
Rabbit Monoclonal Antibody
Clone ID: EP2529Y
Swiss Prot: P35609
Mol Weight: 100kDa
Size: 100ul
Description
Alpha-actinin is a ubiquitously expressed protein found in numerous actin structures. It consists of an N-terminal actin binding domain, a central rod domain, and a C-terminal domain and functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments and also serves as an interaction site for several cytoskeletal and signaling proteins (1). Alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibers, while ACTN3 expression is restricted to a subset of type 2 fibers (2).
Recommended Applications
WB, IHC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:200,000-1,000,000
IHC: 1:100-250
IP: 1:40
FC: 1:100
Species Reactivity
Human, Mouse, Rat
Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only
Products Data
![]() |
![]() |
Specificity
A synthetic peptide corresponding to residues on the N-terminus of human Alpha-Actinin 2 was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ACTN2 antibody, CMD1AA antibody, Alpha-actinin-2 antibody, Alpha-actinin skeletal muscle isoform 2 antibody, F-actin cross-linking protein antibody
Description References
1. Ylanne J, et al. Structure 9(7):597-604, 2001
2. Mills M et al. Hum Mol Genet 10(13): 1335-46, 2001
相关产品
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
3-D Life Dextran-PEG Hydrogel Kit
3-D Life Dextran-CD Hydrogel Kit(3D 细胞培养 葡聚糖马来酰亚胺-聚乙二醇仿生水凝胶试剂盒)
3-D水凝胶PEG-Link(聚乙二醇交联剂)(3D细胞培养 PEG 交联物(非降解))
3-D Life CD-Link(3D细胞培养 CD 交联物(可细胞降解))
3-D Life Maleimide-Dextran Set(3D 细胞培养葡聚糖马来酰亚胺聚合物)
3D 细胞培养RGD多肽(粘附剂)3-D Life RGD Peptide
3-D Life Scrambled RGD Peptide
Pig C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Mouse C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Human C-type lectin domain family 5 member A(CLEC5A)ELISA kit
无形体IgM免疫荧光试剂盒
牛甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
鸡甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
人羰基还原酶-4(CBR4)
1820
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
Dulbecco’s Modified Eagle Medium (D-MEM) (1X), liquid (high glucose)
面议
详细地址
关注
拨打电话
留言咨询