Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody|100ul|2243-1-上海希美化学有限公司

产品详情

Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody
Cat.#: 2243-1
Rabbit Monoclonal Antibody
Clone ID: EP1334(2)Y
Swiss Prot: P68363
Mol Weight: 52kDa
Size: 100ul

Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. An essential component of microtubules, alpha-tubulin is also a multigene family in many species (1). Familial amyloidosis, British type, is an autosomal dominant disease characterized by progressive dementia, spastic paralysis and ataxia. The identity of the accumulating amyloid is not known, thus preventing the definitive classification of the disease. Findings suggest that the C-terminal fragments of both alpha- and beta-tubulin are closely associated to the amyloid deposits of familial amyloidosis, British type (2).

Recommended Applications
WB, ICC

Applications and Recommended Dilution Factors
WB: 1:25,000
ICC: 1:50 - 100

Species Reactivity
Human

Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on Jurkat cell lysates using anti-Phospho-Alpha-Tubulin (p272) RabMAb (cat. #2243-1), 1:50,000 dilution. Cells were either (A) untreated (B) treated with pervanadate.

Specificity
A phospho synthetic peptide corresponding to residues surrounding tyrosine 272 of human alpha-tubulin was used as an immunogen. This antibody detects alpha-tubulin phosphorylated at tyrosine 272.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
TUBA1B antibody, K-ALPHA-1 antibody, Tubulin alpha-1B chain antibody, Alpha-tubulin ubiquitous antibody, Tubulin K-alpha-1 antibody, Tubulin alpha-ubiquitous chain antibody

Description References
1. Cowan NJ et al. Mol Cell Biol 3(10):1738-45, 1983
2. Baumann MH, et al. Biochem Biophys Res Commun 219(6):238-42.

Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody由上海希美化学有限公司为您提供，货号2243-1，规格：100ul，CAS号：，如您想了解更多关于Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody价格、Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody结构式、批发、用途等信息，欢迎咨询。除供应Alpha-Tubulin Phospho(pY272)(TUBA1B)antibody外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：
规格：	100ul
货号：	2243-1
CAS号：