AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody|100ul|3450-1-上海希美化学有限公司

产品详情

AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody
Cat.#: 3450-1
Rabbit Monoclonal Antibody
Clone ID: EPR3052
Swiss Prot: P54646
Mol Weight: 62kDa
Size: 100ul

Description
AMPK alpha 2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000

Species Reactivity
Human, Mouse, Rat

Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on 293T cell lysates using anti-Phospho-AMPK alpha 2 (pS491) RabMAb (cat. #3450-1). Cells were either (A) untreated (B) treated with Lambda Phosphatase (LP).

Specificity
A phospho specific peptide corresponding to residues surrounding Serine 491 of human AMPK alpha 2 was used as an immunogen. This antibody only detects AMPK alpha 2 phosphorylated at Serine 491.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
PRKAA2 antibody, AMPK antibody, AMPK2 antibody, PRKAA antibody, 5'-AMP-activated protein kinase catalytic subunit alpha-2 antibody, antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.

AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody由上海希美化学有限公司为您提供，货号3450-1，规格：100ul，CAS号：，如您想了解更多关于AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody价格、AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody结构式、批发、用途等信息，欢迎咨询。除供应AMPK alpha 2 Phospho(pS491)(PRKAA2)antibody外，还可为您提供Recombinant Human Zinc-Alpha 2 Glycoprotein(ZA2G)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

Business information

工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：
规格：	100ul
货号：	3450-1
CAS号：