APP(Abeta40)antibody|100ul|2238-1-上海希美化学有限公司

APP(Abeta40)antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

2238-1

CAS号：

产品详情

APP(Abeta40)antibody
Cat.#: 2238-1
Rabbit Monoclonal Antibody
Clone ID: EP1876Y
Swiss Prot: P05067
Mol Weight: 4kDa
Size: 100ul

Description
Alzheimer's disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Aβ4) protein has been found to be the principal constituent of senile plaques of ADs patients (1-2). APP (Abeta40) is proteolytically cleaved to generate the 4 kDa Aβ4 protein. Two variants of Aβ4 can be detected; Aβ-40 short-tailed and Aβ-42 long-tailed (3-4).

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000

Species Reactivity
Human

Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on 5ng of recombinant protein using anti-APP (Abeta40) RabMAb (cat. # 2238-1).
B. Western blot analysis on A. Abeta40, B. Abeta42 and C. Abeta38 using anti-APP (Abeta40) RabMAb (cat. # 2238-1).

Specificity
A synthetic peptide corresponding to residues in human APP (Abeta40) was used as immunogen. This antibody specifically recognizes Amyloid Beta Protein (Aβ4) variant Aβ-40.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
APP antibody, AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN2 antibody, C31 antibody, Gamma-CTF(50) antibody

Description References
1. Glenner, G. G, et al. (1984) Biochem. Biophys. Res. Commun. 120, 885-890
2. Masters, C. L., et al. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4245-4249
3. Dovey, H., et al. (1993) NeuroReport 4, 1039-1042
4. Vigo-Pelfrey, C., et al (1993) J. Neurochem. 61, 1965-1968

Business information

工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】