Atg3(ATG3)antibody|100ul|3580-1-上海希美化学有限公司

Atg3(ATG3)antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

3580-1

CAS号：

产品详情

Atg3(ATG3)antibody
Cat.#: 3580-1
Rabbit Monoclonal Antibody
Clone ID: EPR4801
Swiss Prot: Q9NT62
Mol Weight: 40kDa
Size: 100ul

Description
Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole (1). Atg3 is an E2-like enzyme involved in autophagy and mitochondrial homeostasis. It catalyzes the conjugation of Atg8-like proteins to phosphatidylethanolamine (PE), which is essential to autophagy. Atg3 also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of Atg12 to itself; Atg12 conjugation to Atg3 plays a role in mitochondrial homeostasis but not in autophagy. Atg7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with Atg3 (2).

Recommended Applications
WB, IHC, ICC

Applications and Recommended Dilution Factors
WB: 1:10,000-50,000
IHC: 1:100 - 250
ICC: 1:100 - 250

Species Reactivity
Human, Mouse, Rat

Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only

Products Data

Western blot analysis on (A) K562, (B) HL-60, (C) HeLa, and (D) Jurkat cell lysates using anti-Atg3 RabMAb (cat. #3580-1).
Immunohistochemical analysis of paraffin-embedded human muscle tissue using anti-Atg3 RabMAb (cat. #3580-1).
Immunofluorescent staining of HeLa cells using anti-Atg3 RabMAb (cat. #3580-1).

Specificity
A synthetic peptide corresponding to residues near the N-terminus in human Atg3 was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ATG3 antibody, APG3 antibody, APG3-LIKE antibody, APG3L antibody, DKFZp564M1178 antibody, FLJ22125 antibody, MGC15201 antibody, PC3-96 antibody, Ubiquitin-like-conjugating enzyme ATG3 antibody, Protein PC3-96 antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
2. The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res. 38:D142-D148 (2010).

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】