ATG4A antibody|100ul|3194-1-上海希美化学有限公司

ATG4A antibody

参考价：¥2750

供货周期：

一周

品牌：

规格：

100ul

货号：

3194-1

CAS号：

产品详情

ATG4A antibody
Cat.#: 3194-1
Rabbit Monoclonal Antibody
Clone ID: EPR4122
Swiss Prot: Q8WYN0
Mol Weight: 45kDa
Size: 100ul

Description
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging (1). ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of target proteins, such as MAP1LC3, GABARAPL2 and GABARAP. ATG4A belongs to the peptidase C54 family, and is widely with high expression level in skeletal muscle and brain (2).

Recommended Applications
WB, IHC, IP

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only

Products Data

Western blot analysis on (A) fetal liver, (B) HepG2, (C) Jurkat, and (D) fetal brain lysates using anti-ATG4A RabMAb (cat. #3194-1).
Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-ATG4A RabMAb (cat. #3194-1).
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using anti-ATG4A RabMAb (cat. #3194-1).

Specificity
A synthetic peptide corresponding to residues in human ATG4A was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ATG4A antibody, APG4A antibody, AUTL2 antibody, Cysteine protease ATG4A antibody, AUT-like 2 cysteine endopeptidase antibody, Autophagin-2 antibody, Autophagy-related cysteine endopeptidase 2 antibody, Autophagy-related protein 4 homolog A antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8.
2. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2010)

Business information

工商信息

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】