Aven(AVEN)antibody

Aven(AVEN)antibody

参考价:¥2750
供货周期: 一周
品牌:
规格: 100ul
货号: 3372-1
CAS号:
上海希美化学有限公司
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Aven(AVEN)antibody
Cat.#: 3372-1
Rabbit Monoclonal Antibody
Clone ID: EPR4720
Swiss Prot: Q9NQS1
Mol Weight: 55kDa
Size: 100ul

Description
Aven is a cell death regulator that interacts with anti-apoptotic protein Bcl-xl (1, 2). It also interacts with and inhibits Apaf-1 oligomerization, required to activate caspase-9. Aven overexpression is associated with poor prognosis in childhood acute lymphoblastic leukemia (1). High expression is found in the testis, ovary, and thymus (2).

Recommended Applications
WB, IHC, ICC, IP

Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
IHC: 1:50 - 100
ICC: 1:100 - 250
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only

Products Data  

 

 

Western blot analysis on (A) Ramos, (B) HeLa, (C) MCF-7, and (D) Raji cell lysates using anti-Aven RabMAb (cat. #3372-1).
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Aven RabMAb (cat. #3372-1).
Immunofluorescent staining of HeLa cells using anti-Aven RabMAb (cat. #3372-1).

Specificity
A synthetic peptide corresponding to residues in human Aven was used as an immunogen.

Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
AVEN antibody, PDCD12 antibody, Cell death regulator Aven antibody, antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
2. The UniProt Consortium. The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 38:D142-D148 (2010). 

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