ADSL Antibody(Center)|100ug|T3470-上海希美化学有限公司

ADSL Antibody(Center)

参考价：¥2890

供货周期：

一周

品牌：

规格：

100ug

货号：

T3470

CAS号：

产品详情

ADSL Antibody(Center)
Cat.#: T3470
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P30566
Mol Weight: 55kDa
Size: 100ug

Description
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human

Products Data

Western blot analysis of ADSL Antibody (Center) in NCI-H460, Hela, Jurkat cell line lysates (35ug/lane). ADSL (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human brain tissue reacted with ADSL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ADSL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174~203 amino acids from the Center region of human ADSL.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Alternative Names
ADSL antibody, AMPS antibody, ASASE antibody, ASL antibody, Adenylosuccinate lyase antibody, Adenylosuccinase antibody

Description References
Stone,R.L., et.al., J. Biol. Chem. 268 (26), 19710-19716 (1993)
Mouchegh,K., et.al., J. Pediatr. 150 (1), 57-61 (2007)

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】