供货周期: | 一周 |
品牌: | |
规格: | 100ul |
货号: | S1911 |
CAS号: |
AKAP12 antibody
Cat.#: S1911
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q02952
Mol Weight: 191.52kDa
Size: 100ul
Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]
Recommended Applications
WB, IHC, ICC
Applications and Recommended Dilution Factors
WB: 1:500-1:3000
IHC: 1:100-1:250,IF:1:100-1:200
ICC: 1:100-1:200
Species Reactivity
Human
Other species have not been tested
Products Data
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Specificity
Synthetic peptide contain a sequence corresponding to a region within amino acids 1719 and 1782 of AKAP12
Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.
Alternative Names
AKAP12 antibody, AKAP250 antibody, DKFZp686M0430 antibody, DKFZp686O0331 antibody, FLJ20945 antibody, FLJ97621 antibody, A-kinase anchor protein 12 antibody, Gravin antibody, Myasthenia gravis autoantigen antibody
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