| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 100ug |
| 货号： | T1931 |
| CAS号： |
AKT2 Antibody(Center)
Cat.#: T1931
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P31751
Mol Weight: 56kDa
Size: 100ug
Description
AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Recommended Applications
WB, ELISA
Applications and Recommended Dilution Factors
WB: 1:100~500
ELISA: 1:1,000
Species Reactivity
Human
Products Data
Western blot analysis of AKT2 (arrow) using rabbit polyclonal AKT2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AKT2 gene (Lane 2) (Origene Technologies).
Specificity
This AKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101~131 amino acids from the center region of human AKT2.
Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Names
AKT2 antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, RAC-beta serine/threonine-protein kinase antibody, RAC-PK-beta antibody
Description References
Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
Yuan, Z.Q., et al., J. Biol. Chem. 278(26):23432-23440 (2003).
Jones, D.T., et al., Blood 101(8):3174-3180 (2003).
Brozinick, J.T. Jr., et al., Diabetes 52(4):935-941 (2003).
Miyakawa, M., et al., Endocr. J. 50(1):77-83 (2003).
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Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
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面议
Dulbecco's Modified Eagle Medium (D-MEM), powder (high glucose)
面议
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面议
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面议
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面议
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面议
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