供货周期: | 一周 |
品牌: | |
规格: | 100ug |
货号: | T1929 |
CAS号: |
AKT2 Antibody(N-term)
Cat.#: T1929
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P31751
Mol Weight: 56kDa
Size: 100ug
Description
AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Recommended Applications
WB, IHC, ELISA
Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:50-100
ELISA: 1:1,000
Species Reactivity
Human, Mouse
Products Data
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Specificity
This AKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101~130 amino acids from the N-terminal region of human AKT2 Antibody.
Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Names
AKT2 antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, RAC-beta serine/threonine-protein kinase antibody, RAC-PK-beta antibody
Description References
George, S., et al., Science 304(5675):1325-1328 (2004).
Xu, X., et al., Oncol. Rep. 11(1):25-32 (2004).
Shim, D., et al., Arch. Biochem. Biophys. 425(2):214-220 (2004).
Li, X., et al., Gastroenterology 126(1):122-135 (2004).
Vojtek, A.B., et al., Mol. Cell. Biol. 23(13):4417-4427 (2003).
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