Mouse Anti SARS Spike

参考价：¥9660

供货周期：

一周

品牌：

规格：

100ug

货号：

ANT-179

CAS号：

产品详情

Catalogue Number

ANT-179

Type

Mouse antibody Monoclonal.

Introduction

SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.

Background

It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.

Contents

100 ug in 200 ul PBS containing 0.2% gelatin and 0.05% sodium azide.

Isotype

Mouse IgG1,k.

Antigen

The antibody was developed using a synthetic peptide from the putative SARS Spike glycoprotein(Genbank accession no.NP_828851)corresponding to amino acids 19-35.

Applications

This monoclonal antibody can be used for detection of SARS Spike protein in western blot analysis at 1-3 ug/ml. The antibody was tested on a cell line transfected with full-length cDNA coding for the SARS Spike protein with a predicted molecular weight of 139 kDa.

:namespace prefix = w />StorageStore at 4C, stable for 6 months. For long-term storage, store at -200C.
Western blot analysis of SARS Spike in (A) transfected mouse melanoma cell lysate and (B) untransfected cell lysate.

Usage

Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» SARS Core (1-49 a.a.)

» SARS Core (1-49,192-220 a.a.)

» SARS Core (340-390 a.a.)

» SARS Envelope

» SARS Matrix

» SARS Mosaic S(C)

» SARS Mosaic S(M)

» SARS Mosaic S(N)

» SARS-CoV

» SARS-Nucleocapsid Antibody

» SARS-Spike Antibody

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】