Polyclonal Anti Anthrax LF

Polyclonal Anti Anthrax LF

参考价：¥8260
供货周期： 一周
品牌：
规格： 200ul
货号： ANT-181
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-181
Type Polyclonal Antibody.
Background Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2).
Contents 100µgs in 200µl PBS containing 0.2% gelatin and 0.05% sodium azide.
Isotype Rabbit Ig.
Antigen The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 47-65 of the Anthrax LF protein (~90 kD).
Applications This polyclonal antibody can be used for detection of Anthrax LF protein in western blot.
Not tested in other applications.
Storage Store at 4C, stable for 6 months. For long-term storage, store at -20C.
  :namespace prefix = w />Western blot analysis of Anthrax LF in recombinant protein at 1:1000 dilution. Lane A shows the pre-bleed.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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