Polyclonal Rabbit Anti HIV-1 gp120

Polyclonal Rabbit Anti HIV-1 gp120

参考价:¥4200
供货周期: 一周
品牌:
规格: 0.1ml
货号: ANT-210
CAS号:
上海希美化学有限公司
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Catalogue Number ANT-210
Synonyms HIV-1 gp120, HIV1gp120, HIV-I gp120, HIVIgp120.
Type Polyclonal Rabbit Antibody.
Introduction Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells.
Description Rabbit Polyclonal Antibody to gp120 (HIV-1) serum.
Host Rabbit.
Formulation Each 0.5ml of Polyclonal Antibody serum was lyophilized in vials.
Immunogen Recombinant HIV-1 gp120 produced in baculovirus expression system.
Stability Stable for 2 yeas at -20o C. Avoid freeze/thaw cycles.
Applications Binds to recombinant HIV-1 gp120 ELISA and Western Blot Optimal dilutions should be determined by the customer, based on titration. Suggested starting dilutions are listed belowWestern Blot: 1-500 to 1-1000.
ELISA : 1:500 to 1000.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Polyclonal Rabbit Anti HIV-1 gp120由上海希美化学有限公司为您提供,货号ANT-210,规格:0.1ml,CAS号:,如您想了解更多关于Polyclonal Rabbit Anti HIV-1 gp120价格、Polyclonal Rabbit Anti HIV-1 gp120结构式、批发、用途等信息,欢迎咨询。除供应Polyclonal Rabbit Anti HIV-1 gp120外,还可为您提供Polyclonal Rabbit Anti HA-tag peptide、Polyclonal Rabbit Anti Human Heparanase-1 (HPA-1)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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