Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）

Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-328
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-328
Synonyms HSF-1, HSF1, HSTF-1, HSTF1, Heat shock factor protein 1, Heat shock transcription factor 1.
Type Mouse Anti Human Monoclonal.
Introduction The transcription of heat-shock genes is rapidly induced after temperature stress in response to environmental changes, and it is also involved in oogenesis, spermatogenesis, and placental development. Hsp90, is a major repressor of HSF1 gene. HSF1 is known for its participation in heat shock response. HSF1 protein regulates the transcription of hundreds of targets, such as genes involved in protein folding, detoxification, energy generation, carbohydrate metabolism, and cell wall organization. HSF1 binds to MTA1 in vitro & in breast carcinoma. Suppression of estrogen-dependent transcription may contribute to role of HSF1 in cancer. Human cancer lines of diverse origins express higher dependence on HSF1 function to maintain proliferation and survival than their non-transformed counterparts. HSF1 induces anticoagulation and relaxation factors in vascular endothelial cells and could therefore be used to treat cardiovascular disease. HSF1 is directly involved in the regulation of HO1 havi
Clone PJ7F9AT.
Immunogen Anti-human HSF1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSF1 amino acids 1-529 purified from E. coli.
Ig Subclass Mouse IgG1 heavy chain and κ light chain.
Purification Method HSF1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications HSF1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000~ 2,000. Recommended starting dilution is 1:1,000.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）由上海希美化学有限公司为您提供，货号ANT-328，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）价格、Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Heat Shock Transcription Factor-1 （HSF1）外，还可为您提供Recombinant Human Heat Shock Transcription Factor-1(HSF1)等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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