Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）

Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-388
CAS号：
上海希美化学有限公司
银牌会员 丨 13年 丨 生产商
关注展位 全部试剂
产品详情

Catalogue Number ANT-388
Synonyms MATA2, MATII, SAMS2, MAT-2A, S-adenosylmethionine synthetase isoform type-2, AdoMet synthetase 2, Methionine adenosyltransferase 2, Methionine adenosyltransferase II, MAT2A, AMS2.
Type Mouse Anti Human Monoclonal.
Introduction MAT2A is an important enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is expressed in extrahepatic tissues. In liver, MAT2A expression associates with growth, dedifferentiation, and cancer. NF-kappa B and AP-1 are necessary for basal MAT2A expression in HepG2 cells and mediate the increase in MAT2A expression in response to TNF-alpha. Up-regulation of MAT2A provides growth improvement and s-adenosylmethionine and methylthioadenosine thus can block mitogenic signaling in colon cancer cells. Lower expression of both MAT2A and MAT2beta and interfere with leptin signaling in liver cancer cells.
Clone PAT3A2AT.
Immunogen Anti-human MAT2A mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAT2A amino acids 1-395 purified from E. coli.
Ig Subclass Mouse IgG2b heavy chain and κ light chain.
Purification Method MAT2A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications MAT2A antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000 ~ 1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
» MAT2A Human

相关产品

同类推荐 更多
Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）由上海希美化学有限公司为您提供，货号ANT-388，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）价格、Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
Business information
工商信息 信息已认证
contact us
联系方式

详细地址

上海市松江区陆家圈路168弄113号
当前位置： 上海希美化学 试剂 Mouse Anti Human Methionine Adenosyltransferase II Alpha （MAT2A）

关注

拨打电话

留言咨询