Mouse Anti MHC Class I (H-2K)

Mouse Anti MHC Class I (H-2K)

参考价：¥2170
供货周期： 一周
品牌：
规格： 500µg
货号： ANT-176
CAS号：
上海希美化学有限公司
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Catalogue Number
ANT-176

Type
Mouse Antibody Monoclonal.

Introduction
MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length, with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino acids, are divided into three globular domains labeled Alpha-1, Alpha-2 and Alpha-3 prime, with Alpha-1 being closest to the amino terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 Microglobulin It links primarily with the Alpha-3 prime domain and is essential for MHC stability.

The MHC ability to show a vast range of antigenic peptides for T cell recognition needs a compromise between broad specificity and high affinity. Both MHC class I and MHC class II show an exceptional structure while the peptide main chain is tightly bound and peptide side chains show less restrictive interactions. It is primarily the peptide side-chain contacts and conformational variability that ensures that the peptide-MHC complex presents an antigenically unique surface to T cell receptors.

Clone
NYRmH-2K.

Immunogen
Purified mouse LN cells (C57Bl/6 anti-BALB/c).

Ig Subclass
Mouse IgG2b.

Specificity
Recognizes most mouse H-2K haplotypes (k,p,q,r,s). Does NOT react with H-2kd.

Purification Method
Ion exchange column.

Protein concentration
1mg/ml in PBS (after reconstitution).

Storage Procedures
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Reconstitution
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4°C.

Antibody Properties
Cytotoxic and staining antibody. For staining, use 10 ml/106 cells. Titer for cytotoxicity should be determined by the investigator.

Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Mouse Anti MHC Class I (H-2K)由上海希美化学有限公司为您提供，货号ANT-176，规格：500µg，CAS号：，如您想了解更多关于Mouse Anti MHC Class I (H-2K)价格、Mouse Anti MHC Class I (H-2K)结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti MHC Class I (H-2K)外，还可为您提供Mouse Anti MHC Class II (I-A) Biotin、Mouse Anti MHC Class II (I-A) FITC等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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