Mouse Anti Human Nicastrin （NCSTN）|20µg|ANT-441-上海希美化学有限公司

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Catalogue Number	ANT-441
Synonyms	Nicastrin, NCSTN, KIAA0253, APH2, RP11-517F10.1.
Type	Mouse Anti Human Monoclonal.
Introduction	Nicastrin is a Type I transmembrane glycoprotein which is an integral component of the multimeric gamma-secretase complex. Nicastrin cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide which is the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer''s disease; however, the nature of the Nicastrin''s role in Alzheimer''s disease is not known for certain.
Clone	PAT3B2AT.
Immunogen	Anti-human NCSTN mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NCSTN amino acids 34-153 purified from E. coli.
Ig Subclass	Mouse IgG2b heavy chain and κ light chain.
Purification Method	NCSTN antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation	1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life	12 months at -20°C. 1 month at 4°C.
Applications	NCSTN antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1000. Recommended starting dilution is 1:500.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Mouse Anti Human Nicastrin （NCSTN）由上海希美化学有限公司为您提供，货号ANT-441，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Nicastrin （NCSTN）价格、Mouse Anti Human Nicastrin （NCSTN）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Nicastrin （NCSTN）外，还可为您提供人分层蛋白（Stratifin）、人骨织素(Ostn)ELISA kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

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企业名称: 上海希美化学有限公司
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信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

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供货周期：	一周
品牌：
规格：	20µg
货号：	ANT-441
CAS号：