Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）

Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-341
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-341
Synonyms Proliferating cell nuclear antigen, PCNA, Cyclin, MGC8367.
Type Mouse Anti Human Monoclonal.
Introduction PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
Clone Pk1A3AT.
Immunogen Anti-human PCNA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PCNA amino acids 1-261 purified from E. coli.
Ig Subclass Mouse IgG3 heavy chain and κ light chain.
Purification Method PCNA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications PCNA antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）由上海希美化学有限公司为您提供，货号ANT-341，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）价格、Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Proliferating Cell Nuclear Antigen （PCNA）外，还可为您提供Mouse Anti Human Betaine Homocysteine S-Methyltransferase （BHMT）、Mouse Anti Human Lys-63-specific deubiquitinase BRCC36 （BRCC3）等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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