Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）

Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-364
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-364
Synonyms PI5, maspin, SERPINB5, serpin peptidase inhibitor clade B (ovalbumin) member 5, Serpin B5, Protease inhibitor 5.
Type Mouse Anti Human Monoclonal.
Introduction SERPINB5 (Maspin) is a tumor suppressor protein of the serine proteinase inhibitor family. Maspin plays a vital role in embryonic development through critical functions in cell adhesion. In addition, Maspin is present in normal breast and prostatic epithelial cells although down regulated in the particular carcinomas. SERPINB5 impedes the growth, invasion, and metastatic properties of mammary tumors as well as the invasive ability of pancreatic ductal adenocarcinoma cells. SERPINB5 being a breast tumor suppressor gene is a significant marker of the disease progression in breast neoplasms. Furthermore, high expression of maspin is linked to squamous cell carcinoma in non-small-cell lung cancer. Moreover, maspin expression has been directly linked with the biological aggressiveness of ovarian carcinoma. Maspin exhibits no serine protease inhibitory activity since it does not undergo the stressed to relaxed conformational transition typical of active serpins.
Clone PAT2N6AT.
Immunogen Anti-human SERPINB5 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SERPINB5 amino acids 1-375 purified from E. coli.
Ig Subclass Mouse IgG2b heavy chain and κ light chain.
Purification Method SERPINB5 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications SERPINB5 antibody has been tested by ELISA, Western blot analysis and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）由上海希美化学有限公司为您提供，货号ANT-364，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）价格、Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5 （SERPINB5）外，还可为您提供重组人塞尔潘肽酶抑制剂(Recombinant Human SERPINB5)、兔抗凝血酶III(SERPINC1)ELISA kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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