Mouse Anti Human Von Hippel-Lindau Protein （VHL）

Mouse Anti Human Von Hippel-Lindau Protein （VHL）

参考价：¥1820
供货周期： 一周
品牌：
规格： 20µg
货号： ANT-316
CAS号：
上海希美化学有限公司
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Catalogue Number ANT-316
Synonyms Von Hippel-Lindau disease tumor suppressor, pVHL, Protein G7, VHL, RCA1, VHL1, HRCA1.
Type Mouse Anti Human Monoclonal.
Introduction Von Hippel-Lindau disease is a dominant inherited syndrome characterized by the predisposition to develop various kinds of benign and malignant tumors, including clear cell renal carcinomas, pheochromocytomas and hemangioblastomas of the central nervous system and retina. VHL syndrome is caused by germline mutation in the VHL tumor suppressor, and VHL tumors are associated with loss or mutation of the remaining wild-type allele. VHL has two domains: a roughly 100-residue NH2-terminal domain rich in  sheet (-domain) and a smaller -helical domain (-domain), held together by two linkers and a polar interface. VHL protein is also involved in the degradation of hypoxia-inducible factor (HIF).
Clone P52A11AT.
Immunogen Anti-human VHL mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human VHL amino acids 1-154 purified from E. coli.
Ig Subclass Mouse IgG2b heavy chain and κ light chain.
Purification Method VHL antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life 12 months at -20°C. 1 month at 4°C.
Applications VHL antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Mouse Anti Human Von Hippel-Lindau Protein （VHL）由上海希美化学有限公司为您提供，货号ANT-316，规格：20µg，CAS号：，如您想了解更多关于Mouse Anti Human Von Hippel-Lindau Protein （VHL）价格、Mouse Anti Human Von Hippel-Lindau Protein （VHL）结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti Human Von Hippel-Lindau Protein （VHL）外，还可为您提供Recombinant Human Von Hippel-Lindau Protein(VHL)、大鼠凝血因子XIV(FXIV/protein C)ELISA Kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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