Recombinant Human 4-1BB Ligand(Human 4-1BBL)

Recombinant Human 4-1BB Ligand(Human 4-1BBL)

参考价：面议
供货周期： 一周
品牌： Prospect Biosystems
规格： 5µg
货号： CYT-649
CAS号：
上海希美化学有限公司
银牌会员 丨 13年 丨 生产商
关注展位 全部试剂
产品详情

4 1BBL Human
4-1BB Ligand Human Recombinant
Catalog No. CYT-649

Synonyms:
CD137L, CD137-L, 4-1BBL, 4-1BB Ligand, TNFSF9, Tumor Necrosis Factor (ligand) Superfamily Member 9.

Introduction:
4-1BBL is a transmembrane cytokine that is part of the tumor necrosis factor (TNF) ligand family. 4-1BBL is a bidirectional signal transducer that performs as a ligand for TNFRSF9, which is a costimulatory receptor molecule in T lymphocytes. TNFSF9 and its TNFRSF9 take part in the antigen presentation development and in the generation of cytotoxic T cells. 4-1BBR is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. TNFSF9 reactivates anergic T lymphocytes as well as promoting T lymphocyte proliferation. 4-1BB Ligand is needed for the optimal CD8 responses in CD8 T cells. 4-1BBL is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with TNFRSF9 strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease.

Description:
TNFSF9 Human Recombinant fused to 37 amino acids His tag at N-terminus produced in E.Coli is a single, non-glycosylated polypeptide chain containing 222 amino acids (71-254 a.a.) and having a molecular mass of 23.8 kDa.
The TNFSF9 His tag fusion protein is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless solution.

Formulation:
Recombinant 4-1BBL contains 20mM Tris buffer pH-8, 100mM NaCl and 20% glycerol.

Stability:
4-1BBL although stable at 10°C for 3 weeks, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by SDS-PAGE.

Amino acid sequence:
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTGGLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRL GVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» 4 1BBR Human

相关试剂 更多

相关产品

同类推荐 更多
Recombinant Human 4-1BB Ligand(Human 4-1BBL)由上海希美化学有限公司为您提供，货号CYT-649，规格：5µg，CAS号：，如您想了解更多关于Recombinant Human 4-1BB Ligand(Human 4-1BBL)价格、Recombinant Human 4-1BB Ligand(Human 4-1BBL)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human 4-1BB Ligand(Human 4-1BBL)外，还可为您提供Recombinant Human 4-1BB Receptor(Human 4-1BBR)、4-1BBL(TNFSF9)antibody等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
Business information
工商信息 信息已认证
contact us
联系方式

详细地址

上海市松江区陆家圈路168弄113号
当前位置： 上海希美化学 试剂 Recombinant Human 4-1BB Ligand(Human 4-1BBL)

关注

拨打电话

留言咨询