重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)

重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 5µg
货号: CHM-353
CAS号:
上海希美化学有限公司
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CCL28 Human
Mucosae-Associated Epithelial Chemokine Human Recombinant (CCL28)
Catalog No. CHM-353
Synonyms:
MEC, CCK1, SCYA28, MGC71902, CCL28, C-C motif chemokine 28, Small-inducible cytokine A28, Mucosae-associated epithelial chemokine, Protein CCK1.

Introduction:
CCL28 is part of the subfamily of small cytokine CC genes. CCL28 shows chemotactic activity for resting CD4 or CD8 T cells and eosinophils. CCL28 binds to chemokine receptors CCR3 and CCR10. CCL28 is involved in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. CCL28 mediates mucosal immunity in HIV exposure and infection. CCL28 is involved in the pathogenesis of inflammatory skin diseases.
Human CCL28 cDNA encodes a 127 amino acid residue precursor protein with a putative 22 amino acid residue signal peptide that is cleaved to produce the 105 amino acid residue mature protein. Human and mouse CCL28 are highly conserved, sharing 83% amino acid identity in their mature regions. CCL28 shares the most homology with CCL27/CTACK. Human and mouse CCL28 RNA expression was found to be highest in normal and pathologic colon with the protein being expressed by epithelial cells. Human CCL28 RNA was also present in normal and asthmatic lung tissues.

Description:
CCL28 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 108 amino acids and having a molecular mass of 12.3 kDa.
The CCL28 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
Lyophilized from a concentrated (1mg/ml) solution in water containing 20mM PBS and 150mM NaCl.

Solubility:
It is recommended to reconstitute the lyophilized CCL28 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized CCL28 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL28 should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY.

Biological Activity:
Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0 -10.0 ng/ml.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)由上海希美化学有限公司为您提供,货号CHM-353,规格:5µg,CAS号:,如您想了解更多关于重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)价格、重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)结构式、批发、用途等信息,欢迎咨询。除供应重组人粘膜相关上皮细胞趋化因子(CCL28)(MEC)外,还可为您提供重组人粘膜相关上皮细胞趋化因子His(MEC His)、人粘膜相关上皮趋化因子(MEC/CCL28)ELISA Kit 等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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