重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)

重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)

参考价：面议
供货周期： 一周
品牌： Prospect Biosystems
规格： 2µg
货号： PKA-353
CAS号：
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ILK1 Human
Integrin Linked Kinase Human Recombinant
Catalog No. PKA-353

Synonyms:
Integrin-linked protein kinase, ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59ILK, ILK, ILK1, ILK2, DKFZp686F1765, P59.

Introduction:
ILK1 (Integrin-linked kinase) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 regulates a number of biological properties which include: anchorage-independent cell cycle progression, tumor cell invasion and apoptosis. ILK1 can also be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Furthermore, ILK1 phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits in addition to several adaptors and signaling proteins, it also acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 is a focal adhesion protein part of the complex ILK-PINCH. This complex is deemed to be one of the convergence points of integrin- and growth factor-signaling pathway. ILK1 is stimulated rapidly but briefly by both cell fibronectin interactions, as well as by insulin, in a PI3-K-dependent manner, probably through the binding of PtdIns(3,4,5)P3 with a PH-like domain of ILK.
ILK1 over-expression has been documented in a wide variety of human malignancies.

Description:
ILK1 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 452 amino acids fragment (1-452) having a total molecular mass of 62kDa and fused with a 4.5kDa amino-terminal hexahistidine tag.
The ILK1 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
ILK1 protein is supplied in 1x PBS and 50% glycerol.

Stability:
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

Purity:
Greater than 95.0% as determined by SDS-PAGE.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)由上海希美化学有限公司为您提供，货号PKA-353，规格：2µg，CAS号：，如您想了解更多关于重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)价格、重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)结构式、批发、用途等信息，欢迎咨询。除供应重组人整合素连接激酶(Human Integrin Linked Kinase/ILK1)外，还可为您提供人整合素连接激酶1(ILK-1)ELISA Kit 、人解整合素样金属蛋白酶9(ADAM9)ELISA Kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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