重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)

重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 2µg
货号: PRO-419
CAS号:
上海希美化学有限公司
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KISS1 Human
KISS-1 Metastasis-Suppressor Human Recombinant
Catalog No. PRO-419

Synonyms:
Kisspeptin-1, KISS-1, METASTIN, Metastasis-suppressor KiSS-1, KISS1, MGC39258.

Introduction:
KISS1 is a metastasis suppressor protein that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity.KISS1 functions to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. KISS1 is involved in the regulation of cell-matrix adhesion. KISS1 plays a role in cytoskeletal reorganization. A polymorphism in the terminal exon of KISS1 mRNA results in two protein isoforms. Expression of KiSS1 is localized to specific regions of the hypothalamus in numerous species and is regulated by gonadal steroids and across the estrous cycle..KISS1 generates a c-terminally amidated peptide, metastin which functions as the endogenous ligand of the g-protein coupled receptor gpr54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis.

Description:
KISS1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids (20-138) and having a molecular mass of 12.6 Dalton.
The KISS1 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless solution

Formulation:
The protein solution (1mg/ml) contains 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.

Stability:
KISS1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Amino Acid Sequence:
MEPLEKVASV GNSRPTGQQL ESLGLLAPGE QSLPCTERKP AATARLSRRG TSLSPPPESS GSPQQPGLSA PHSRQIPAPQ GAVLVQREKD LPNYNWNSFG LRFGKREAAP GNHGRSAGRG

Purity:
Greater than 90.0% as determined by SDS-PAGE.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)由上海希美化学有限公司为您提供,货号PRO-419,规格:2µg,CAS号:,如您想了解更多关于重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)价格、重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)结构式、批发、用途等信息,欢迎咨询。除供应重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KISS1)外,还可为您提供人含免疫球蛋白样环和上皮生长因子样域酪氨酸激酶2(Tie-2)ELISA Kit、重组人杀伤细胞免疫球蛋白样受体(Recombinant Human KIR2DL1)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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